General Information

  • ID:  hor002468
  • Uniprot ID:  A0A161R9R0
  • Protein name:  NdWFamide
  • Gene name:  NA
  • Organism:  Aplysia californica (California sea hare)
  • Family:  NA
  • Source:  Animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Aplysia (genus), Aplysiidae (family), Aplysioidea (superfamily), Aplysiida (order), Tectipleura, Euthyneura, Heterobranchia (subclass), Gastropoda (class), Mollusca (phylum), Lophotrochozoa, Spiralia, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  NWF
  • Length:  3(24-26)
  • Propeptide:  MSRALAAVTVVFLLSVVCSPTSANWFGKRGDKDDLFSLLLQQQQQQPTHADSSIVPLASTGAEDAMFAIENIVQAWRQHRSEKLGRSTQG
  • Signal peptide:  MSRALAAVTVVFLLSVVCSPTSA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-A0A161R9R0-F1(AlphaFold_DB_ID)

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor002468_AF2.pdbhor002468_ESM.pdb

Physical Information

Mass: 50136 Formula: C24H27N5O5
Absent amino acids: ACDEGHIKLMPQRSTVY Common amino acids: FNW
pI: 6.11 Basic residues: 0
Polar residues: 1 Hydrophobic residues: 2
Hydrophobicity: -53.33 Boman Index: -133
Half-Life: 1.4 hour Half-Life Yeast: 3 min
Half-Life E.Coli: >10 hour Aliphatic Index 0
Instability Index: -2790 Extinction Coefficient cystines: 5500
Absorbance 280nm: 2750

Literature

  • PubMed ID:  21388150
  • Title:  Distinguishing Endogenous D-amino Acid-Containing Neuropeptides in Individual Neurons Using Tandem Mass Spectrometry