HORDB

ID: hor002321
Uniprot ID: P01362
Protein name: Beta-bag cell peptide
Gene name: NA
Organism: Aplysia californica (California sea hare)
Family: Molluscan ELH family
Source: animal
Expression: Bag cell neurons.
Disease: NA
Comments: NA
Taxonomy: Aplysia (genus), Aplysiidae (family), Aplysioidea (superfamily), Aplysiida (order), Tectipleura, Euthyneura, Heterobranchia (subclass), Gastropoda (class), Mollusca (phylum), Lophotrochozoa, Spiralia, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005179 hormone activity
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Sequence: RLRFH
Length: 5
Propeptide: MKRPNNRPTNTMSLILCLTLSSLCVSSQSASVHGKNFATNRAVKSSSPFVVLSPDDNVVSMSGENGYRSALREAFDKSSRDYDDNGEDVFSNEKRRLRFHKRRLRFDRRDQDEGNFRRFPTNAVSMSADENSPFDLSNEDGAVYQRDLRAPRLRFYSLRKRAAGGMEQSEGQNPETESHSRRKRSVLTPSLSSLGESLESGISKRISINQDLKAITDMLLTEQIRERQRYLADLRQRLLEKGKRSSGVSLLTSNKDEEQRELLKAISNLLD
Signal peptide: MKRPNNRPTNTMSLILCLTLSSLCVSSQ
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Function: Specifically excites 2 neurons, L1 and R1, in the abdominal ganglion.
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
kd: NA
Half life: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor002321_AF2.pdb

hor002321_ESM.pdb

Mass:	79939	Formula:	C33H53N13O6
Absent amino acids:	ACDEGIKMNPQSTVWY	Common amino acids:	R
pI:	12.5	Basic residues:	3
Polar residues:	0	Hydrophobic residues:	2
Hydrophobicity:	-112	Boman Index:	-2660
Half-Life:	1 hour	Half-Life Yeast:	2 min
Half-Life E.Coli:	2 min	Aliphatic Index	78
Instability Index:	4652	Extinction Coefficient cystines:	0
Absorbance 280nm:	0