General Information

  • ID:  hor002291
  • Uniprot ID:  NA
  • Protein name:  Hydra-LWamide
  • Gene name:  NA
  • Organism:  Hydra vulgaris
  • Family:  LWamide neuropeptide family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  EQPGLW
  • Length:  6
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  T6 Tryptophan amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor002291_AF2.pdbhor002291_ESM.pdb

Physical Information

Mass: 81817 Formula: C34H48N8O10
Absent amino acids: ACDFHIKMNRSTVY Common amino acids: EGLPQW
pI: 3.85 Basic residues: 0
Polar residues: 1 Hydrophobic residues: 2
Hydrophobicity: -101.67 Boman Index: -416
Half-Life: 1 hour Half-Life Yeast: 30 min
Half-Life E.Coli: >10 hour Aliphatic Index 65
Instability Index: 11200 Extinction Coefficient cystines: 5500
Absorbance 280nm: 1100

Literature

  • PubMed ID:  9048780
  • Title:  Molecular Cloning of a Preprohormone From Hydra Magnipapillata Containing Multiple Copies of Hydra-L Wamide (Leu-Trp-NH2) Neuropeptides: Evidence for Processing at Ser and Asn Residues