General Information

  • ID:  hor002277
  • Uniprot ID:  NA
  • Protein name:  Kisspeptin
  • Gene name:  NA
  • Organism:  NA
  • Family:  KISS1 family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  YNWNSFGLRY
  • Length:  10
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Be an important regulator of reproductive behavior and gonadotrophin secretion
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor002277_AF2.pdbhor002277_ESM.pdb

Physical Information

Mass: 148014 Formula: C63H82N16O16
Absent amino acids: ACDEHIKMPQTV Common amino acids: NY
pI: 9.17 Basic residues: 1
Polar residues: 6 Hydrophobic residues: 3
Hydrophobicity: -96 Boman Index: -2071
Half-Life: 2.8 hour Half-Life Yeast: 10 min
Half-Life E.Coli: 2 min Aliphatic Index 39
Instability Index: 2179 Extinction Coefficient cystines: 8480
Absorbance 280nm: 942.22

Literature

  • PubMed ID:  20301214
  • Title:  beta-Sheet Aggregation of kisspeptin-10 Is Stimulated by Heparin but Inhibited by Amphiphiles