General Information

  • ID:  hor002251
  • Uniprot ID:  A0A6J1WYP4
  • Protein name:  Hez-kinin-2
  • Gene name:  LOC113520395
  • Organism:  Galleria mellonella (Greater wax moth)
  • Family:  Kinin family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Galleria (genus), Galleriinae (subfamily), Pyralidae (family), Pyraloidea (superfamily), Obtectomera, Ditrysia, Heteroneura (parvorder), Neolepidoptera (infraorder), Glossata (suborder), Lepidoptera (order), Amphiesmenoptera (superorder), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  VRFSPWG
  • Length:  7
  • Propeptide:  MSHHWLLITFSWFGIARLQHISTGGPGADAVLDNVDSTLHYPLPYINYFSLPRNDFENYQNDASNSENYNQYYHMSEHGQSDLQRKRRTAEDKEEVKDKRWLPNLVDTDKTIYLHNDEMIGNPFLAAFSNREDENATDMNILEPLDKKSFSPWGGKRDKPNIENVWTWKRASNMREPSMPKRVRFSPWGGKRNGQMVYKPSSKGSKIIFLSTMPEVTRVVSNFSPNGERFDLAGFQFVPSLDKRHPIKILALSTKLDEKTLKEALPFKTFLESLPKIYKPGHPYLDVSLKKDGKRKVKFSAWGGKRSPPIIGPMWTPASSDMTESTLNTILLIRKNQDDQILKAL
  • Signal peptide:  MSHHWLLITFSWFGIARL
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-A0A6J1WYP4-F1(AlphaFold_DB_ID)

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor002251_AF2.pdbhor002251_ESM.pdb

Physical Information

Mass: 95516 Formula: C41H57N11O9
Absent amino acids: ACDEHIKLMNQTY Common amino acids: FGPRSVW
pI: 10.55 Basic residues: 1
Polar residues: 2 Hydrophobic residues: 3
Hydrophobicity: -17.14 Boman Index: -803
Half-Life: 100 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 41.43
Instability Index: 5241.43 Extinction Coefficient cystines: 5500
Absorbance 280nm: 916.67

Literature

  • PubMed ID:  15706623
  • Title:  Mass Spectrometric Analysis of Head Ganglia and Neuroendocrine Tissue of Larval Galleria Mellonella (Arthropoda, Insecta)