General Information

  • ID:  hor002249
  • Uniprot ID:  NA
  • Protein name:  Cus-DP-3
  • Gene name:  NA
  • Organism:  Culex salinarius
  • Family:  Kinin family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  TKYVSKQFFSWG
  • Length:  12
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  T12 Glycine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor002249_AF2.pdbhor002249_ESM.pdb

Physical Information

Mass: 167405 Formula: C72H100N16O18
Absent amino acids: ACDEHILMNPR Common amino acids: FKS
pI: 10.25 Basic residues: 2
Polar residues: 5 Hydrophobic residues: 4
Hydrophobicity: -53.33 Boman Index: -1288
Half-Life: 7.2 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 24.17
Instability Index: 1397.5 Extinction Coefficient cystines: 6990
Absorbance 280nm: 635.45

Literature

  • PubMed ID:  9350979
  • Title:  Isolation and Structural Elucidation of Eight Kinins From the Retrocerebral Complex of the American Cockroach, Periplaneta Americana