General Information

  • ID:  hor002236
  • Uniprot ID:  NA
  • Protein name:  Achetakinin V
  • Gene name:  NA
  • Organism:  Locusta migratoria
  • Family:  Kinin family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  AFHSWG
  • Length:  6
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  T6 Glycine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  May be important in the stimulation of ion transport and inhibition of diuretic activity in Malpighian tubules
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor002236_AF2.pdbhor002236_ESM.pdb

Physical Information

Mass: 79312 Formula: C34H41N9O8
Absent amino acids: CDEIKLMNPQRTVY Common amino acids: AFGHSW
pI: 7.55 Basic residues: 1
Polar residues: 2 Hydrophobic residues: 3
Hydrophobicity: -11.67 Boman Index: 0
Half-Life: 4.4 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 16.67
Instability Index: -895 Extinction Coefficient cystines: 5500
Absorbance 280nm: 1100

Literature

  • PubMed ID:  1585017
  • Title:  Locustakinin, a Novel Myotropic Peptide From Locusta Migratoria, Isolation, Primary Structure and Synthesis