HORDB

ID: hor001927
Uniprot ID: Q09169
Protein name: Growth hormone-releasing factor
Gene name: adcyap1
Organism: Pelophylax ridibundus (Marsh frog) (Rana ridibunda)
Family: Glucagon family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Pelophylax (genus), Ranidae (family), Ranoidea (superfamily), Neobatrachia (suborder), Anura (order), Batrachia (superorder), Amphibia (class), Tetrapoda, Dipnotetrapodomorpha, Sarcopterygii (superclass), Euteleostomi, Teleostomi, Gnathostomata, Vertebrata, Craniata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005179 hormone activity; GO:0005184 neuropeptide hormone activity
GO BP: GO:0007165 signal transduction
GO CC: GO:0005576 extracellular region

Sequence: HADDLLNKAYRNLLGQLSARKYLHTLMAKHLGAVSSSLEDDSEPLS
Length: 46(79-124)
Propeptide: MYRKALLVWLLVYGIMRCTVHSSPTALKYPALRLEDEVYDEDGNTLPDFAFDNNPIGIGNPASVFDDMYSFYYPAEKRHADDLLNKAYRNLLGQLSARKYLHTLMAKHLGAVSSSLEDDSEPLSKRHSDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRIKNKGRRVAYL
Signal peptide: MYRKALLVWLLVYGIMRCTVHS
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor001927_AF2.pdb

hor001927_ESM.pdb

Mass:	588259	Formula:	C221H358N64O71S
Absent amino acids:	CFIW	Common amino acids:	L
pI:	6.8	Basic residues:	8
Polar residues:	13	Hydrophobic residues:	16
Hydrophobicity:	-41.74	Boman Index:	-8452
Half-Life:	3.5 hour	Half-Life Yeast:	10 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	101.96
Instability Index:	3641.09	Extinction Coefficient cystines:	2980
Absorbance 280nm:	66.22