HORDB

ID: hor001748
Uniprot ID: P41875
Protein name: Neuropeptide PF4
Gene name: NA
Organism: Panagrellus redivivus (Microworm)
Family: FARP (FMRFamide related peptide) family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Panagrellus (genus), Panagrolaimidae (family), Panagrolaimoidea (superfamily), Panagrolaimomorpha (infraorder), Tylenchina (suborder), Rhabditida (order), Chromadorea (class), Nematoda (phylum), Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Function: Myoactive; induces a rapid concentration-dependent muscle tension increase.
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: 0.1 n M
ED50: NA
kd: NA
Half life: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor001748_AF2.pdb

hor001748_ESM.pdb

Mass:	102830	Formula:	C45H68N12O9
Absent amino acids:	ACDEGHLMQSTVWY	Common amino acids:	F
pI:	11.65	Basic residues:	2
Polar residues:	1	Hydrophobic residues:	3
Hydrophobicity:	-48.57	Boman Index:	-1623
Half-Life:	1.3 hour	Half-Life Yeast:	3 min
Half-Life E.Coli:	2 min	Aliphatic Index	55.71
Instability Index:	-2367.14	Extinction Coefficient cystines:	0
Absorbance 280nm:	0

PubMed ID: 7716079
Title: Isolation and preliminary biological characterization of KPNFIRFamide, a novel FMRFamide-related peptide from the free-living nematode, Panagrellus redivivus.