HORDB

ID: hor001590
Uniprot ID: Q07981
Protein name: KQDPFLRI-amide
Gene name: NA
Organism: Cornu aspersum (Brown garden snail) (Helix aspersa)
Family: FARP (FMRFamide related peptide) family
Source: Animal
Expression: Central nervous system.
Disease: NA
Comments: NA
Taxonomy: Cornu (subgenus), Cornu (genus), Helicidae (family), Helicoidea (superfamily), Helicina, Stylommatophora (order), Eupulmonata (superorder), Panpulmonata, Euthyneura, Heterobranchia (subclass), Gastropoda (class), Mollusca (phylum), Lophotrochozoa, Spiralia, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Sequence: QDPFLRI
Length: 7(69-75)
Propeptide: MTSLCLTIAPAVLSLICLSSYGWAEGDTTDNEYLRFGRENNNGYIRFGRNDPFLRFGKKSDPFLRFGKQDPFLRIGRQDPFLRFGKQDPFLRFGKQDPFLRIGKQDPFLRFGRSEPYLRFGRNDPYLRFGRNDPYLRFGRNDPYLRFGRNDPYLRFGKNDPFLRFGKSVDGEIEAGVDAVTLSREHEFAHENAASDRQKRSAYTDAIDKDNSLTSLVREAREASDSNGQINDGKVVEVPVFRDTRNGHYMRFGKK
Signal peptide: MTSLCLTIAPAVLSLICLS
Modification: T7 Isoleucine amide
Glycosylation: NA
Mutagenesis: NA

Function: Can function as both cardioregulatory hormones and transmitters and may regulate cardiovascular function.
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
kd: NA
Half life: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor001590_AF2.pdb

hor001590_ESM.pdb

Mass:	99524	Formula:	C41H65N11O11
Absent amino acids:	ACEGHKMNSTVWY	Common amino acids:	DFILPQR
pI:	6.34	Basic residues:	1
Polar residues:	0	Hydrophobic residues:	3
Hydrophobicity:	-28.57	Boman Index:	-1636
Half-Life:	0.8 hour	Half-Life Yeast:	10 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	111.43
Instability Index:	9111.43	Extinction Coefficient cystines:	0
Absorbance 280nm:	0