HORDB

ID: hor001444
Uniprot ID: A2TLI1
Protein name: Gonadotropin-inhibitory hormone
Gene name: NA
Organism: Taeniopygia guttata (Zebra finch) (Poephila guttata)
Family: FARP (FMRFamide related peptide) family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Taeniopygia (genus), Estrildinae (subfamily), Estrildidae (family), Passeroidea (superfamily), Passeriformes (order), Neognathae (infraclass), Aves (class), Coelurosauria, Theropoda, Saurischia, Dinosauria, Archosauria, Archelosauria, Sauria, Sauropsida, Amniota, Tetrapoda, Dipnotetrapodomorpha, Sarcopterygii (superclass), Euteleostomi, Teleostomi, Gnathostomata, Vertebrata, Craniata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Sequence: SIKPFSNLPLRF
Length: 12(51-62)
Propeptide: EEKQRSLNFEEMEDWRSKDIIKMNPFAASKMPNSVANLPLRFGRNYPEERSIKPFSNLPLRFGRAFGENIRNHAPKVSHRLERSPLVKGSSQSLLNLPQRFGKSLPVNLPRDVEEFEPGI
Signal peptide: NA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor001444_AF2.pdb

hor001444_ESM.pdb

Mass:	161507	Formula:	C68H107N17O16
Absent amino acids:	ACDEGHMQTVWY	Common amino acids:	FLPS
pI:	11.65	Basic residues:	2
Polar residues:	3	Hydrophobic residues:	5
Hydrophobicity:	8.33	Boman Index:	-1319
Half-Life:	1.9 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	97.5
Instability Index:	4395.83	Extinction Coefficient cystines:	0
Absorbance 280nm:	0

PubMed ID: 22045661
Title: Identification, expression, and physiological functions of Siberian hamster gonadotropin-inhibitory