General Information

  • ID:  hor001434
  • Uniprot ID:  P83322
  • Protein name:  SIFamide
  • Gene name:  NA
  • Organism:  Penaeus monodon (Giant tiger prawn)
  • Family:  FARP (FMRFamide related peptide) family
  • Source:  Animal
  • Expression:  brain and thoracic ganglion
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Penaeus (genus), Penaeidae (family), Penaeoidea (superfamily), Dendrobranchiata (suborder), Decapoda (order), Eucarida (superorder), Eumalacostraca (subclass), Malacostraca (class), Multicrustacea (superclass), Crustacea (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  GO:0003674 molecular_function
  • GO BP:  GO:0007218 neuropeptide signaling pathway
  • GO CC:  GO:0005575 cellular_component; GO:0005576 extracellular region

Sequence Information

  • Sequence:  GYRKPPFNGS
  • Length:  10(1-10)
  • Propeptide:  GYRKPPFNGSIF
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor001434_AF2.pdbhor001434_ESM.pdb

Physical Information

Mass: 128294 Formula: C51H75N15O14
Absent amino acids: ACDEHILMQTVW Common amino acids: GP
pI: 10.45 Basic residues: 2
Polar residues: 5 Hydrophobic residues: 1
Hydrophobicity: -152 Boman Index: -2579
Half-Life: 30 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 0
Instability Index: -45 Extinction Coefficient cystines: 1490
Absorbance 280nm: 165.56

Literature

  • PubMed ID:  21459120
  • Title:  Visualization of Neuropeptides in Paraffin-Embedded Tissue Sections of the Central Nervous System in the Decapod Crustacean, Penaeus Monodon, by Imaging Mass Spectrometry