HORDB

ID: hor001379
Uniprot ID: A0A8J5MJP5
Protein name: FMRFamide-related peptide
Gene name: NA
Organism: Homarus americanus (American lobster)
Family: FARP (FMRFamide related peptide) family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Homarus (genus), Nephropidae (family), Nephropoidea (superfamily), Astacidea (infraorder), Pleocyemata (suborder), Decapoda (order), Eucarida (superorder), Eumalacostraca (subclass), Malacostraca (class), Multicrustacea (superclass), Crustacea (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Sequence: YSDRNYLRF
Length: 9(82-90)
Propeptide: MIVAAWVLLTTLTWCCQAHAAPVPPVVAALDPPTDALLPAQSQEDDLFALPEKRLLKYFLPASQAWGGDAYPIGQEGTKRGYSDRNYLRFGRSDTNDYEGEEMPESPEKRNRNFLRFGRDQNRNFLRFGRSGSPMEFATDLQEDVELPVEEKRGAHKNYLRFGRGNRNFLRFGRGDRNFLRFGRSVDRQLSSLSCEDCDEEQKAREFTSTPSPTTIQPLARTKRDVSAVLSDDSIESSVLRQINAHRIKRAAAQN
Signal peptide: MIVAAWVLLTTLTWCCQAHA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor001379_AF2.pdb

hor001379_ESM.pdb

Mass:	137621	Formula:	C56H80N16O16
Absent amino acids:	ACEGHIKMPQTVW	Common amino acids:	RY
pI:	9.17	Basic residues:	2
Polar residues:	4	Hydrophobic residues:	2
Hydrophobicity:	-142.22	Boman Index:	-4098
Half-Life:	2.8 hour	Half-Life Yeast:	10 min
Half-Life E.Coli:	2 min	Aliphatic Index	43.33
Instability Index:	3562.22	Extinction Coefficient cystines:	2980
Absorbance 280nm:	372.5

PubMed ID: 20025296
Title: Mass Spectral Analysis of Neuropeptide Expression and Distribution in the Nervous System of the Lobster Homarus Americanus