General Information

  • ID:  hor001308
  • Uniprot ID:  NA
  • Protein name:  RFamide
  • Gene name:  NA
  • Organism:  Cancer borealis
  • Family:  FMRFamide related peptide family
  • Source:  Animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  GGRNFLRF
  • Length:  8
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  T8 Phenylalanine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:   NA
  • IC50:  NA
  • EC50:  NA
  • ED50:  NA
  • Kd:  NA
  • Half life:  NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor001308_AF2.pdbhor001308_ESM.pdb

Physical Information

Mass: 109114 Formula: C44H67N15O10
Absent amino acids: ACDEHIKMPQSTVWY Common amino acids: FGR
pI: 12.5 Basic residues: 2
Polar residues: 3 Hydrophobic residues: 3
Hydrophobicity: -48.75 Boman Index: -2372
Half-Life / Aliphatic Index: 30 hour Aliphatic Index: 48.75
Instability Index: 4488.75 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  18700782
  • Title:  Combining Microdialysis, NanoLC-MS, and MALDI-TOF/TOF to Detect Neuropeptides Secreted in the Crab, Cancer Borealis