General Information

  • ID:  hor001296
  • Uniprot ID:  NA
  • Protein name:  RFamide
  • Gene name:  NA
  • Organism:  Callinectes sapidus
  • Family:  FMRFamide related peptide family
  • Source:  Animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  GHRNFLRF
  • Length:  8
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  T8 Phenylalanine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:   NA
  • IC50:  NA
  • EC50:  NA
  • ED50:  NA
  • Kd:  NA
  • Half life:  NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor001296_AF2.pdbhor001296_ESM.pdb

Physical Information

Mass: 117123 Formula: C48H71N17O10
Absent amino acids: ACDEIKMPQSTVWY Common amino acids: FR
pI: 12.5 Basic residues: 3
Polar residues: 2 Hydrophobic residues: 3
Hydrophobicity: -83.75 Boman Index: -2932
Half-Life / Aliphatic Index: 30 hour Aliphatic Index: 48.75
Instability Index: 2946.25 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  21740068
  • Title:  Discovery and Characterization of the Crustacean Hyperglycemic Hormone Precursor Related Peptides (CPRP) and Orcokinin Neuropeptides in the Sinus Glands of the Blue Crab Callinectes Sapidus Using Multiple Tandem Mass Spectrometry Techniques