HORDB

ID: hor001154
Uniprot ID: D9I8P2
Protein name: Neuropeptide AF34
Gene name: AFP-13
Organism: Ascaris suum (Pig roundworm) (Ascaris lumbricoides)
Family: FARP (FMRFamide related peptide) family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Ascaris (genus), Ascarididae (family), Ascaridoidea (superfamily), Ascaridomorpha (infraorder), Spirurina (suborder), Rhabditida (order), Chromadorea (class), Nematoda (phylum), Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Sequence: DSKLMDPLIRF
Length: 11(59-69)
Propeptide: MAINSISCLITMLAITVAVSTLESSEIRMLESEFLDGKRGNSYRSFFNPNEYTVVERRDSKLMDPLIRFGKRTNIMGENRLNRNLRAEGLSSPLIRFGKRTPPEEDLLGRFTRDPQQRIVTDETVLRFGRSSAPAAA
Signal peptide: MAINSISCLITMLAITVAVSTLES
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor001154_AF2.pdb

hor001154_ESM.pdb

Mass:	151315	Formula:	C60H99N15O17S
Absent amino acids:	ACEGHNQTVWY	Common amino acids:	DL
pI:	6.45	Basic residues:	2
Polar residues:	1	Hydrophobic residues:	4
Hydrophobicity:	-9.09	Boman Index:	-2122
Half-Life:	1.1 hour	Half-Life Yeast:	3 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	106.36
Instability Index:	1888.18	Extinction Coefficient cystines:	0
Absorbance 280nm:	0

PubMed ID: 21524146
Title: Discovery of Neuropeptides in the Nematode Ascaris Suum by Database Mining and Tandem Mass Spectrometry