HORDB

ID: hor001145
Uniprot ID: D2XV90
Protein name: Aplysia FRF-A
Gene name: NA
Organism: Aplysia californica (California sea hare)
Family: FMRFamide related peptide family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Aplysia (genus), Aplysiidae (family), Aplysioidea (superfamily), Aplysiida (order), Tectipleura, Euthyneura, Heterobranchia (subclass), Gastropoda (class), Mollusca (phylum), Lophotrochozoa, Spiralia, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: NA
GO CC: NA

Sequence: GGALFRF
Length: 7(125-131)
Propeptide: MEPRPITLSLAVLLAALCTTCATGSAKLVSSSEDNTNSHTDGLTRDHQPQKRSAAAILSPADDALLVRADEGEEEGVGGSYPGIPLSLPGTADKRSTLFRFGKRGAGTLFRFGKRGSLFRFGKRGGALFRFGKRGGALFRFGKRGVASGSGAFPLADDSDVKRTLFRFGKRSNLDLLRDVLSQYQLSAYPDAYPDAYPDAYIDDVDSKRGVDGFHWGDDQ
Signal peptide: MEPRPITLSLAVLLAALCTTCATGSA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor001145_AF2.pdb

hor001145_ESM.pdb

Mass:	87410	Formula:	C37H54N10O8
Absent amino acids:	CDEHIKMNPQSTVWY	Common amino acids:	FG
pI:	10.55	Basic residues:	1
Polar residues:	2	Hydrophobic residues:	4
Hydrophobicity:	84.29	Boman Index:	-35
Half-Life:	30 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	70
Instability Index:	1407.14	Extinction Coefficient cystines:	0
Absorbance 280nm:	0

PubMed ID: 15715658
Title: LFRFamides: A Novel Family of Parasitation-Induced -RFamide Neuropeptides That Inhibit the Activity of Neuroendocrine Cells in Lymnaea Stagnalis