General Information

  • ID:  hor001142
  • Uniprot ID:  A0A7M7L8Y0
  • Protein name:  TWKSPDIVIRFa–FMRFa-like
  • Gene name:  100578542
  • Organism:  Apis mellifera (Honeybee)
  • Family:  FMRFamide related peptide family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Apis (genus), Apini (tribe), Apinae (subfamily), Apidae (family), Apoidea (superfamily), Aculeata (infraorder), Apocrita (suborder), Hymenoptera (order), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  AGFKNLNREQ
  • Length:  10
  • Propeptide:  MSCLSSLYVLPFICNCVLVSSSVLTTLKTDGGLRIFKDAPNEFKDVPNEFEEALKRHSIDCHSDKRENPQGCSGSFFVRDERSDPDRGKERFYNGDGDRGSNRSPRTWKSPDIVIRFGRAGFKNLNREQKRGRNDLNFIRYGRGMQIYPDSVVTAICSNLLSNEDIQPYEARLLRFCNCLNNNDVDHRENLDFFEDRLGTKHD
  • Signal peptide:  MSCLSSLYVLPFICNCVLVSS
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-A0A7M7L8Y0-F1(AlphaFold_DB_ID)

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor001142_AF2.pdbhor001142_ESM.pdb

Physical Information

Mass: 133701 Formula: C50H81N17O16
Absent amino acids: CDHIMPSTVWY Common amino acids: N
pI: 9.69 Basic residues: 2
Polar residues: 3 Hydrophobic residues: 3
Hydrophobicity: -144 Boman Index: -3545
Half-Life: 4.4 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 49
Instability Index: 1323 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  19576913
  • Title:  Mass Spectrometric Profiling of (Neuro)-Peptides in the Worker Honeybee, Apis Mellifera