HORDB

General Information

ID: hor001117
Uniprot ID: NA
Protein name: Tyr-FMRFamide
Gene name: NA
Organism: Rattus norvegicus
Family: FMRFamide related peptide family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: NA
GO MF: NA
GO BP: NA
GO CC: NA

Sequence Information

Sequence: YFMRF
Length: 5
Propeptide: NA
Signal peptide: NA
Modification: T5 Phenylalanine amide
Glycosylation: NA
Mutagenesis: NA

Activity

Function: NA
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
Kd: NA
Half life: NA

Structure

Disulfide bond: NA
Structure ID: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor001117_AF2.pdb

hor001117_ESM.pdb

Physical Information

Mass:	83444	Formula:	C38H50N8O7S
Absent amino acids:	ACDEGHIKLNPQSTVW	Common amino acids:	F
pI:	9.35	Basic residues:	1
Polar residues:	1	Hydrophobic residues:	2
Hydrophobicity:	34	Boman Index:	-675
Half-Life / Aliphatic Index:	2.8 hour	Aliphatic Index:	0
Instability Index:	-708	Extinction Coefficient cystines:	1490
Absorbance 280nm:	372.5

Literature

PubMed ID: 7937312
Title: Low affinity of FMRFamide and four FaRPs (FMRFamide-related peptides), including the mammalian-derived FaRPs F-8-Famide (NPFF) and A-18-Famide, for opioid m, d, k1, k2a, or k2b receptors.