HORDB

General Information

ID: hor001113
Uniprot ID: NA
Protein name: Pol-RFamide 2
Gene name: NA
Organism: Polyorchis penicillatus
Family: FMRFamide related peptide family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: NA
GO MF: NA
GO BP: NA
GO CC: NA

Sequence Information

Sequence: EWLKGRF
Length: 7
Propeptide: NA
Signal peptide: NA
Modification: T7 Phenylalanine amide
Glycosylation: NA
Mutagenesis: NA

Activity

Function: NA
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
Kd: NA
Half life: NA

Structure

Disulfide bond: NA
Structure ID: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor001113_AF2.pdb

hor001113_ESM.pdb

Physical Information

Mass:	104229	Formula:	C45H66N12O10
Absent amino acids:	ACDHIMNPQSTVY	Common amino acids:	EFGKLRW
pI:	9.69	Basic residues:	2
Polar residues:	1	Hydrophobic residues:	3
Hydrophobicity:	-94.29	Boman Index:	-1611
Half-Life / Aliphatic Index:	1 hour	Aliphatic Index:	55.71
Instability Index:	-1952.86	Extinction Coefficient cystines:	5500
Absorbance 280nm:	916.67

Literature

PubMed ID: 7909659
Title: The primary structure of the Pol-RFamide neuropeptide precursor protein from the hydromedusa Polyorchis penicillatus indicates a novel processing proteinase activity