HORDB

General Information

ID: hor001090
Uniprot ID: NA
Protein name: FMRFamide-related peptide
Gene name: NA
Organism: Locusta migratoria
Family: FMRFamide related peptide family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: NA
GO MF: NA
GO BP: NA
GO CC: NA

Sequence Information

Sequence: GQERNFLRF
Length: 9
Propeptide: NA
Signal peptide: NA
Modification: T9 Phenylalanine amide
Glycosylation: NA
Mutagenesis: NA

Activity

Function: Have an inhibitory effect, decreasing the amplitude of neurally evoked spermathecal contractions.
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
kd: NA
Half life: NA

Structure

Disulfide bond: NA
Structure ID: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor001090_AF2.pdb

hor001090_ESM.pdb

Physical Information

Mass:	130917	Formula:	C52H79N17O14
Absent amino acids:	ACDHIKMPSTVWY	Common amino acids:	FR
pI:	10.4	Basic residues:	2
Polar residues:	2	Hydrophobic residues:	3
Hydrophobicity:	-116.67	Boman Index:	-3701
Half-Life:	30 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	43.33
Instability Index:	4870	Extinction Coefficient cystines:	0
Absorbance 280nm:	0

Literature

PubMed ID: 11897379
Title: Evidence for the Association of FMRFamide-related Peptides With the Spermatheca of Locusta Migratoria