General Information

  • ID:  hor001066
  • Uniprot ID:  B2ZSS7
  • Protein name:  FMRFamide-related peptide
  • Gene name:  NA
  • Organism:  Haliotis asinina (Donkey's ear abalone) (Ass's ear abalone)
  • Family:  FARP (FMRFamide related peptide) family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Haliotis (genus), Haliotidae (family), Haliotoidea (superfamily), Lepetellida (order), Vetigastropoda (subclass), Gastropoda (class), Mollusca (phylum), Lophotrochozoa, Spiralia, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  GO:0007218 neuropeptide signaling pathway
  • GO CC:  GO:0005576 extracellular region

Sequence Information

  • Sequence:  SDPDLDDVIRASLLAYSLDDSPNN
  • Length:  24
  • Propeptide:  MRPWTSVALLAVVLIKWISCINGFSDFCNKPVNSRICAILSGGPPQNEEKRFLRFGRTLAGDSFLRFGRQFYRIGKDGDDMEKRFLRFGRSDPDLDDVIRASLLAYSLDDSPNNRRRRSVATAPVEAKAVEAGNKDIEKRDADELTSEDKRFMRFGRSGEDEKRFMRFGKSGEEEKRFMRFGKSGDAEKRFMRFGRAGEEEKRFMRFGRAGEDEKRFMRFGKSGEEEKRFMRFGRAGEDGEEIEDEDEGIEADKRFMRFGRDGEDEKRFMRFGKSGEDEKRFMRFGKRFMRFGRDGQDKRFMRFGKRFMRFGKRDSGEGSSEKAETAES
  • Signal peptide:  MRPWTSVALLAVVLIKWISCING
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-B2ZSS7-F1(AlphaFold_DB_ID)
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor001066_AF2.pdbhor001066_ESM.pdb

Physical Information

Mass: 301620 Formula: C110H173N29O44
Absent amino acids: CEFGHKMQTW Common amino acids: D
pI: 3.45 Basic residues: 1
Polar residues: 7 Hydrophobic residues: 8
Hydrophobicity: -52.92 Boman Index: -6200
Half-Life: 1.9 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 101.67
Instability Index: 3277.5 Extinction Coefficient cystines: 1490
Absorbance 280nm: 64.78

Literature

  • PubMed ID:  21452226
  • Title:  Molecular Analysis of Two FMRFamide-encoding Transcripts Expressed During the Development of the Tropical Abalone Haliotis Asinina