General Information

  • ID:  hor001049
  • Uniprot ID:  NA
  • Protein name:  Cyanea-RFamide 1
  • Gene name:  NA
  • Organism:  Cyanea lamarckii
  • Family:  FMRFamide related peptide family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  EWLRGRF
  • Length:  7
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  T7 Phenylalanine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Neurotransmitters
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor001049_AF2.pdbhor001049_ESM.pdb

Physical Information

Mass: 107030 Formula: C45H66N14O10
Absent amino acids: ACDHIKMNPQSTVY Common amino acids: R
pI: 10.4 Basic residues: 2
Polar residues: 1 Hydrophobic residues: 3
Hydrophobicity: -102.86 Boman Index: -2548
Half-Life: 1 hour Half-Life Yeast: 30 min
Half-Life E.Coli: >10 hour Aliphatic Index 55.71
Instability Index: 2011.43 Extinction Coefficient cystines: 5500
Absorbance 280nm: 916.67

Literature

  • PubMed ID:  9245726
  • Title:  Isolation of Three Novel Neuropeptides, the Cyanea-RFamides I–III, from Scyphomedusae