General Information

  • ID:  hor001048
  • Uniprot ID:  NA
  • Protein name:  FMRFamide-like neuropeptide 4
  • Gene name:  NA
  • Organism:  Cancer productus
  • Family:  FMRFamide related peptide family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  TNRNFLRF
  • Length:  8
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  T8 Phenylalanine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Modulation of muscle contraction
  • Mechanism:  NA
  • Cross BBB:  NO
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor001048_AF2.pdbhor001048_ESM.pdb

Physical Information

Mass: 119224 Formula: C48H74N16O12
Absent amino acids: ACDEGHIKMPQSVWY Common amino acids: FNR
pI: 12.5 Basic residues: 2
Polar residues: 3 Hydrophobic residues: 3
Hydrophobicity: -91.25 Boman Index: -3481
Half-Life: 7.2 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 48.75
Instability Index: 1067.5 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  18719922
  • Title:  Characteristic differences in modulation of stomatogastric musculature by a neuropeptide in three species of Cancer crabs