General Information

  • ID:  hor001041
  • Uniprot ID:  NA
  • Protein name:  Neuropeptide AF10
  • Gene name:  NA
  • Organism:  Caenorhabditis elegans
  • Family:  FMRFamide related peptide family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  GFGDEMSMPGVLRF
  • Length:  14
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  T14 Phenylalanine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Decreased the body length and increased the number of body waveforms
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor001041_AF2.pdbhor001041_ESM.pdb

Physical Information

Mass: 177484 Formula: C68H103N17O20S2
Absent amino acids: ACHIKNQTWY Common amino acids: G
pI: 4.18 Basic residues: 1
Polar residues: 4 Hydrophobic residues: 4
Hydrophobicity: 16.43 Boman Index: -1141
Half-Life: 30 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 48.57
Instability Index: 8581.43 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  11087928
  • Title:  Changes in locomotory behavior and cAMP produced in Ascaris suum by neuropeptides from Ascaris suum or Caenorhabditis elegans