HORDB

ID: hor000904
Uniprot ID: P09859
Protein name: Gastrin
Gene name: NA
Organism: Gallus gallus (Chicken)
Family: Gastrin/cholecystokinin family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Gallus (genus), Phasianinae (subfamily), Phasianidae (family), Galliformes (order), Galloanserae (superorder), Neognathae (infraclass), Aves (class), Coelurosauria, Theropoda, Saurischia, Dinosauria, Archosauria, Archelosauria, Sauria, Sauropsida, Amniota, Tetrapoda, Dipnotetrapodomorpha, Sarcopterygii (superclass), Euteleostomi, Teleostomi, Gnathostomata, Vertebrata, Craniata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005179 hormone activity
GO BP: GO:0007165 signal transduction; GO:0007586 digestion
GO CC: GO:0005576 extracellular region

Sequence: FLPHVFAELSDRKGFVQGNGAVEALHDHFYPDWMDF
Length: 36(58-93)
Propeptide: MKTKVFLGLILSAAVTACLCRPAAKAPGGSHRPTSSLARRDWPEPPSQEQQQRFISRFLPHVFAELSDRKGFVQGNGAVEALHDHFYPDWMDFGRRSTEDAADAA
Signal peptide: MKTKVFLGLILSAAVTACLC
Modification: T30 Sulfotyrosine;T36 Phenylalanine amide
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor000904_AF2.pdb

hor000904_ESM.pdb

Mass:	481815	Formula:	C196H271N49O53S
Absent amino acids:	CIT	Common amino acids:	F
pI:	4.69	Basic residues:	5
Polar residues:	6	Hydrophobic residues:	15
Hydrophobicity:	-22.5	Boman Index:	-4396
Half-Life:	1.1 hour	Half-Life Yeast:	3 min
Half-Life E.Coli:	2 min	Aliphatic Index	65
Instability Index:	1371.94	Extinction Coefficient cystines:	6990
Absorbance 280nm:	199.71

PubMed ID: 3743781
Title: Isolation From Chicken Antrum, and Primary Amino Acid Sequence of a Novel 36-residue Peptide of the gastrin/CCK Family