General Information

  • ID:  hor000842
  • Uniprot ID:  E9H4H6
  • Protein name:  Ecdysis-triggering hormone 1
  • Gene name:  ETH
  • Organism:  Daphnia pulex (Water flea)
  • Family:  NA
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Daphnia (genus), Daphniidae (family), Anomopoda (infraorder), Cladocera (suborder), Diplostraca (order), Phyllopoda (subclass), Branchiopoda (class), Crustacea (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  DPSPEPFNPNYNRFRQKIPRI
  • Length:  21
  • Propeptide:  MYRELIMIKGLFLTWLLLASALSDPSPEPFNPNYNRFRQKIPRIGRRGEGIIAEYMNSESFPHEGSLSNFFLKASKAVPRLGRRKDISTESGRAAMVGEEPFGRISNEIPIMNQKQDLWPNMNINELTGALNKELNYPGPRIPKDLQDNYIQDLIHSWINQYENLNEN
  • Signal peptide:  MYRELIMIKGLFLTWLLLASA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-E9H4H6-F1(AlphaFold_DB_ID)
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor000842_AF2.pdbhor000842_ESM.pdb

Physical Information

Mass: 294279 Formula: C117H177N35O32
Absent amino acids: ACGHLMTVW Common amino acids: P
pI: 10.44 Basic residues: 4
Polar residues: 5 Hydrophobic residues: 4
Hydrophobicity: -161.43 Boman Index: -7904
Half-Life: 1.1 hour Half-Life Yeast: 3 min
Half-Life E.Coli: >10 hour Aliphatic Index 37.14
Instability Index: 6503.33 Extinction Coefficient cystines: 1490
Absorbance 280nm: 74.5

Literature

  • PubMed ID:  21830762
  • Title:  Genomics, Transcriptomics, and Peptidomics of Daphnia Pulex Neuropeptides and Protein Hormones