HORDB

ID: hor000807
Uniprot ID: Q17AN4
Protein name: Corazonin precursor-related peptide
Gene name: Crz
Organism: Aedes aegypti (Yellowfever mosquito) (Culex aegypti)
Family: Corazonin family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Stegomyia (subgenus), Aedes (genus), Aedini (tribe), Culicinae (subfamily), Culicidae (family), Culicoidea (superfamily), Culicomorpha (infraorder), Nematocera (suborder), Diptera (order), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005184 neuropeptide hormone activity; GO:0071858 corazonin receptor binding
GO BP: GO:0007218 neuropeptide signaling pathway; GO:0045823 positive regulation of heart contraction
GO CC: GO:0005576 extracellular region

Sequence: SSPEQTAPSRTLLPHIPLGMDKPDEECRLLIQ
Length: 32(35-66)
Propeptide: MKHVFSTSLIVSLFVIFTDAQTFQYSRGWTNGKRSSPEQTAPSRTLLPHIPLGMDKPDEECRLLIQRFLKSPCDVRLANAIVNRNKDLLRDMADDVNDGTALLYDPVPMVDTAASEDVRFKRGTPDRRLLNDGMHRL
Signal peptide: MKHVFSTSLIVSLFVIFTDA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor000807_AF2.pdb

hor000807_ESM.pdb

Mass:	412622	Formula:	C154H255N43O50S2
Absent amino acids:	FNVWY	Common amino acids:	LP
pI:	4.66	Basic residues:	4
Polar residues:	7	Hydrophobic residues:	8
Hydrophobicity:	-58.13	Boman Index:	-6352
Half-Life:	1.9 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	88.44
Instability Index:	9434.69	Extinction Coefficient cystines:	0
Absorbance 280nm:	0