HORDB

ID: hor000612
Uniprot ID: P82153
Protein name: Cydiastatin-2
Gene name: NA
Organism: Cydia pomonella (Codling moth)
Family: Allatostatin family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Cydia (genus), Grapholitini (tribe), Olethreutinae (subfamily), Tortricidae (family), Tortricoidea (superfamily), Apoditrysia, Ditrysia, Heteroneura (parvorder), Neolepidoptera (infraorder), Glossata (suborder), Lepidoptera (order), Amphiesmenoptera (superorder), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Function: A potent inhibitor of the spontaneous contractions of the foregut and the oesophageal valve
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
kd: NA
Half life: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

AF-P82153-F1.pdb

hor000612_AF2.pdb

hor000612_ESM.pdb

Mass:	247285	Formula:	C104H149N23O28
Absent amino acids:	CDHIMQTW	Common amino acids:	Y
pI:	8.98	Basic residues:	2
Polar residues:	8	Hydrophobic residues:	6
Hydrophobicity:	-20	Boman Index:	-1763
Half-Life:	4.4 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	81.11
Instability Index:	4711.67	Extinction Coefficient cystines:	5960
Absorbance 280nm:	350.59