HORDB

ID: hor000521
Uniprot ID: A0A0L0C6U5
Protein name: Allatostatin-5
Gene name: NA
Organism: Lucilia cuprina (Green bottle fly) (Australian sheep blowfly)
Family: Allatostatin family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Lucilia (genus), Luciliinae (subfamily), Calliphoridae (family), Oestroidea (superfamily), Calyptratae, Schizophora, Cyclorrhapha, Eremoneura, Muscomorpha (infraorder), Brachycera (suborder), Diptera (order), Endopterygota (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005184 neuropeptide hormone activity
GO BP: GO:0007165 signal transduction
GO CC: NA

Sequence: DPLNEERRANRYGFGL
Length: 16(161-176)
Propeptide: MNKRFVSLLMLACWLSVAYSEPSYEDTASQVNSPNGGHQANSLFNTNADSNMDGDNMDGMIMGAGLGNKDNYDKRVERYAFGLGRRAYTYTNGGNGIKRLPVYNFGLGKRARPYSFGLGKRSDYEDSDAQIAEDLDRAYNAAFMMDEKRNRPYSFGLGKRDPLNEERRANRYGFGLGRR
Signal peptide: MNKRFVSLLMLACWLSVAYS
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor000521_AF2.pdb

hor000521_ESM.pdb

Mass:	217480	Formula:	C82H127N27O26
Absent amino acids:	CHIKMQSTVW	Common amino acids:	R
pI:	6.58	Basic residues:	3
Polar residues:	5	Hydrophobic residues:	4
Hydrophobicity:	-140.63	Boman Index:	-6401
Half-Life:	1.1 hour	Half-Life Yeast:	3 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	55
Instability Index:	5553.13	Extinction Coefficient cystines:	1490
Absorbance 280nm:	99.33

PubMed ID: 23280433
Title: Neuropeptidomics of the Australian Sheep Blowfly Lucilia Cuprina (Wiedemann) and Related Diptera