General Information

  • ID:  hor000504
  • Uniprot ID:  B7P1Q1
  • Protein name:  Allatostatin-C
  • Gene name:  8053917
  • Organism:  Ixodes scapularis (Black-legged tick) (Deer tick)
  • Family:  Allatostatin family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  Ixodes (genus), Ixodinae (subfamily), Ixodidae (family), Ixodoidea (superfamily), Ixodida (order), Parasitiformes (superorder), Acari (subclass), Arachnida (class), Chelicerata (subphylum), Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  SGWKQCSFNAVSCF
  • Length:  14(81-94)
  • Propeptide:  MASTMKIFVLTGAILLVFGLTGAQVADESGVRSSGVGLGTGGNGISLENMLWNYFMAKQMSRQAQLQRDGEIPTELQRKRSGWKQCSFNAVSCFGRK
  • Signal peptide:  MASTMKIFVLTGAILLVFGLTGA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  AF-B7P1Q1-F1(AlphaFold_DB_ID)
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor000504_AF2.pdbhor000504_ESM.pdb

Physical Information

Mass: 179582 Formula: C69H98N18O20S2
Absent amino acids: DEHILMPRTY Common amino acids: S
pI: 8.23 Basic residues: 1
Polar residues: 7 Hydrophobic residues: 5
Hydrophobicity: 14.29 Boman Index: -1029
Half-Life: 1.9 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 27.86
Instability Index: 5291.43 Extinction Coefficient cystines: 5625
Absorbance 280nm: 432.69

Literature

  • PubMed ID:  19540946
  • Title:  The Neuropeptidomics of Ixodes Scapularis Synganglion