HORDB

ID: hor000490
Uniprot ID: A0A8J5JRR7
Protein name: Allatostatin A
Gene name: AstA-L1
Organism: Homarus americanus (American lobster)
Family: Allatostatin family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Homarus (genus), Nephropidae (family), Nephropoidea (superfamily), Astacidea (infraorder), Pleocyemata (suborder), Decapoda (order), Eucarida (superorder), Eumalacostraca (subclass), Malacostraca (class), Multicrustacea (superclass), Crustacea (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005184 neuropeptide hormone activity
GO BP: GO:0007165 signal transduction
GO CC: NA

Sequence: PRNYAFGL
Length: 8(215-222)
Propeptide: MVGEHGGLGTCVLVVVVLLLTTTTTTAHDYLEDLDDPDTSRLLDVLQYYDTEPSYLYDYGKRHSNYGFGLGKRTPGYAFGLGKREGLYSLGLDKRSDLYSFGLGKKSGSYNFGLGKRSVGDLPEVSKVEDGASPRTKRDVSITEDTLEDKRAKYSFGIGKRESSKNKRSKLYGFGLGKRDSGEERREDDDMENRTQQYSFGLGKQDPDMEIEKRPRNYAFGLGKRESDEDSDKRSQMYSFGLGKRDPDMDMDKRP
Signal peptide: MVGEHGGLGTCVLVVVVLLLTTTTTTA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor000490_AF2.pdb

hor000490_ESM.pdb

Mass:	106210	Formula:	C44H64N12O11
Absent amino acids:	CDEHIKMQSTVW	Common amino acids:	AFGLNPRY
pI:	9.35	Basic residues:	1
Polar residues:	3	Hydrophobic residues:	3
Hydrophobicity:	-36.25	Boman Index:	-1105
Half-Life:	>20 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	?	Aliphatic Index	61.25
Instability Index:	4435	Extinction Coefficient cystines:	1490
Absorbance 280nm:	212.86

PubMed ID: 22860213
Title: Mass Spectral Charting of Neuropeptidomic Expression in the Stomatogastric Ganglion at Multiple Developmental Stages of the Lobster Homarus Americanus