General Information

  • ID:  hor000325
  • Uniprot ID:  NA
  • Protein name:  Allatostatin C
  • Gene name:  NA
  • Organism:  Drosophila melanogaster
  • Family:  Allatostatin family
  • Source:  Animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  EVRYRQCYFNPISCF
  • Length:  15
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Decreases heart rate
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:   NA
  • IC50:  NA
  • EC50:  NA
  • ED50:  NA
  • Kd:  NA
  • Half life:  NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA

  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
    •    hor000325_AF2.pdbhor000325_ESM.pdb

Physical Information

Mass: 217509 Formula: C87H125N23O23S2
Absent amino acids: ADGHKLMTW Common amino acids: CFRY
pI: 8.21 Basic residues: 2
Polar residues: 6 Hydrophobic residues: 4
Hydrophobicity: -34.67 Boman Index: -3503
Half-Life / Aliphatic Index: 1 hour Aliphatic Index: 45.33
Instability Index: 2066 Extinction Coefficient cystines: 3105
Absorbance 280nm: 221.79

Literature

  • PubMed ID:  12479379
  • Title:  The Effects of Three Drosophila Melanogaster Myotropins on the Frequency of Foregut Contractions Differ