HORDB

General Information

ID: hor000284
Uniprot ID: NA
Protein name: Bradykinin
Gene name: NA
Organism: Amia calva
Family: Bradykinin family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: NA
GO MF: NA
GO BP: NA
GO CC: NA

Sequence Information

Sequence: APPGWSPFR
Length: 9
Propeptide: NA
Signal peptide: NA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Activity

Function: May play a role in cardiovascular regulation in holosteans
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
kd: NA
Half life: NA

Structure

Disulfide bond: NA
Structure ID: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor000284_AF2.pdb

hor000284_ESM.pdb

Physical Information

Mass:	115701	Formula:	C49H67N13O11
Absent amino acids:	CDEHIKLMNQTVY	Common amino acids:	P
pI:	10.55	Basic residues:	1
Polar residues:	2	Hydrophobic residues:	3
Hydrophobicity:	-75.56	Boman Index:	-1026
Half-Life:	4.4 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	11.11
Instability Index:	13562.22	Extinction Coefficient cystines:	5500
Absorbance 280nm:	687.5

Literature

PubMed ID: 7651903
Title: Isolation and Biological Activity of [Trp5]bradykinin From the Plasma of the Phylogenetically Ancient Fish, the Bowfin and the Longnosed Gar