General Information

  • ID:  hor000283
  • Uniprot ID:  NA
  • Protein name:  Bradykinin
  • Gene name:  NA
  • Organism:  Acipenseriformes
  • Family:  Bradykinin family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  MPPGMSPFR
  • Length:  9
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Fall in arterial blood pressure;relaxation of tension of vascular rings
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: 4.7+/-0.7*10(-10)M
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor000283_AF2.pdbhor000283_ESM.pdb

Physical Information

Mass: 116210 Formula: C45H70N12O11S2
Absent amino acids: ACDEHIKLNQTVWY Common amino acids: P
pI: 10.55 Basic residues: 1
Polar residues: 2 Hydrophobic residues: 1
Hydrophobicity: -43.33 Boman Index: -970
Half-Life: 30 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 0
Instability Index: 19815.56 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  9622017
  • Title:  Purification and Cardiovascular Activity of [Met1, Met5]-bradykinin From the Plasma of a Sturgeon (Acipenseriformes)