General Information

  • ID:  hor000261
  • Uniprot ID:  NA
  • Protein name:  Gastrin-releasing peptide
  • Gene name:  NA
  • Organism:  Canine
  • Family:  Bombesin/neuromedin-B/ranatensin family
  • Source:  animal
  • Expression:  intestinal muscle
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  GNHWAVGHLM
  • Length:  10
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  NA
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor000261_AF2.pdbhor000261_ESM.pdb

Physical Information

Mass: 128201 Formula: C50H72N16O12S
Absent amino acids: CDEFIKPQRSTY Common amino acids: GH
pI: 7.72 Basic residues: 2
Polar residues: 3 Hydrophobic residues: 4
Hydrophobicity: 1 Boman Index: 137
Half-Life: 30 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 78
Instability Index: -2589 Extinction Coefficient cystines: 5500
Absorbance 280nm: 611.11

Literature

  • PubMed ID:  6853532
  • Title:  Amino Acid Sequences of Three Bombesin-Like Peptides From Canine Intestine Extracts