HORDB

ID: hor000149
Uniprot ID: Q9GT02
Protein name: CHH precursor-related peptide
Gene name: NA
Organism: Carcinus maenas (Common shore crab) (Green crab)
Family: Arthropod CHH/MIH/GIH/VIH hormone family
Source: Animal
Expression: sinus gland
Disease: NA
Comments: NA
Taxonomy: Carcinus (genus), Carcinidae (family), Portunoidea (superfamily), Heterotremata, Eubrachyura, Brachyura (infraorder), Pleocyemata (suborder), Decapoda (order), Eucarida (superorder), Eumalacostraca (subclass), Malacostraca (class), Multicrustacea (superclass), Crustacea (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005179 hormone activity; GO:0005184 neuropeptide hormone activity
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Sequence: TSPMEPSAALAVEHGTTHPLE
Length: 21(44-64)
Propeptide: MYSKTIPAMLAIITVAYLCPLPHAHARSTPGYGRMDRILAALKTSPMEPSAALAVEHGTTHPLEKKQIYDTSCKGVYDRALFNDLEHVCDDCYNLYRTSYVASACRNNCFENEVFDVCVYELYFP
Signal peptide: MYSKTIPAMLAIITVAYLCPLPHAHA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor000149_AF2.pdb

hor000149_ESM.pdb

Mass:	253231	Formula:	C93H147N25O33S
Absent amino acids:	CDFIKNQRWY	Common amino acids:	AEPT
pI:	4.47	Basic residues:	2
Polar residues:	6	Hydrophobic residues:	6
Hydrophobicity:	-31.9	Boman Index:	-2166
Half-Life:	7.2 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	65.24
Instability Index:	3125.71	Extinction Coefficient cystines:	0
Absorbance 280nm:	0

PubMed ID: 19523386
Title: Characterization of the Carcinus Maenas Neuropeptidome by Mass Spectrometry and Functional Genomics