HORDB

ID: hor000147
Uniprot ID: Q9GT03
Protein name: CHH precursor-related peptide
Gene name: NA
Organism: Carcinus maenas (Common shore crab) (Green crab)
Family: Arthropod CHH/MIH/GIH/VIH hormone family
Source: animal
Expression: sinus gland
Disease: NA
Comments: NA
Taxonomy: Carcinus (genus), Carcinidae (family), Portunoidea (superfamily), Heterotremata, Eubrachyura, Brachyura (infraorder), Pleocyemata (suborder), Decapoda (order), Eucarida (superorder), Eumalacostraca (subclass), Malacostraca (class), Multicrustacea (superclass), Crustacea (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005179 hormone activity; GO:0005184 neuropeptide hormone activity
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Sequence: RSTQGYGRMDRILAALKTSPMEPSAALAVEHGTTHPLE
Length: 38
Propeptide: MYSKTIPAMLAIITVAYLCTLPHAHARSTQGYGRMDRILAALKTSPMEPSAALAVEHGTTHPLEKRQIYDTSCKGVYDRALFNDLEHVCDDCYNLYRTSYVASACRNNCFENEVFDVCVYQLYFPNHE
Signal peptide: MYSKTIPAMLAIITVAYLCTLPHAHA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor000147_AF2.pdb

hor000147_ESM.pdb

Mass:	475379	Formula:	C175H287N53O56S2
Absent amino acids:	CFNW	Common amino acids:	A
pI:	7.71	Basic residues:	6
Polar residues:	11	Hydrophobic residues:	11
Hydrophobicity:	-45	Boman Index:	-6973
Half-Life:	1 hour	Half-Life Yeast:	2 min
Half-Life E.Coli:	2 min	Aliphatic Index	72.11
Instability Index:	2770.79	Extinction Coefficient cystines:	1490
Absorbance 280nm:	40.27

PubMed ID: 19523386
Title: Characterization of the Carcinus Maenas Neuropeptidome by Mass Spectrometry and Functional Genomics