General Information

  • ID:  hor000131
  • Uniprot ID:  NA
  • Protein name:  Cerebellin-4
  • Gene name:  NA
  • Organism:  Coturnix coturnix japonica
  • Family:  Cerebellins family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  SKVAFSAVRSTN
  • Length:  12
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  NA
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Exerts neuromodulatory functions
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor000131_AF2.pdbhor000131_ESM.pdb

Physical Information

Mass: 146279 Formula: C54H91N17O18
Absent amino acids: CDEGHILMPQWY Common amino acids: S
pI: 11.65 Basic residues: 2
Polar residues: 5 Hydrophobic residues: 5
Hydrophobicity: -1.67 Boman Index: -2520
Half-Life: 1.9 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 65
Instability Index: 2618.33 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  20298575
  • Title:  Neuropeptidomic Analysis of the Embryonic Japanese Quail Diencephalon