HORDB

ID: hor000082
Uniprot ID: Q07662
Protein name: Vasotocin
Gene name: NA
Organism: Oncorhynchus masou (Cherry salmon) (Masu salmon)
Family: Vasopressin/oxytocin family
Source: Animal
Expression: hypothalamus
Disease: NA
Comments: NA
Taxonomy: Oncorhynchus (genus), Salmoninae (subfamily), Salmonidae (family), Salmoniformes (order), Protacanthopterygii, Euteleosteomorpha (cohort), Clupeocephala, Osteoglossocephalai, Teleostei (infraclass), Neopterygii (subclass), Actinopteri (class), Actinopterygii (superclass), Euteleostomi, Teleostomi, Gnathostomata, Vertebrata, Craniata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005179 hormone activity; GO:0005185 neurohypophyseal hormone activity
GO BP: GO:0007165 signal transduction
GO CC: GO:0005576 extracellular region

Sequence: CYIQNCPRG
Length: 9(21-29)
Propeptide: MPDSTIPLLCVLGLLALSSACYIQNCPRGGKRSFPDLKRPCMSCGPGNRGLCFGPSICCGEGMGCYMGSPEAASCVEENYLTSPCEVGGRVCGSEEGHCAAPGVCCDAESCLLDSDCLDDSKRQPPSEQYSSLMEGLAGDLLQWMLHATRRERPQ
Signal peptide: MPDSTIPLLCVLGLLALSSA
Modification: T9 Glycine amide
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

AF-P01179-F1.pdb

hor000082_AF2.pdb

hor000082_ESM.pdb

Mass:	119610	Formula:	C43H68N14O13S2
Absent amino acids:	ADEFHKLMSTVW	Common amino acids:	C
pI:	8.22	Basic residues:	1
Polar residues:	5	Hydrophobic residues:	1
Hydrophobicity:	-58.89	Boman Index:	-1882
Half-Life:	1.2 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	43.33
Instability Index:	927.78	Extinction Coefficient cystines:	1615
Absorbance 280nm:	201.88

PubMed ID: 1369229
Title: Cloning and Sequence Analyses of Vasotocin and Isotocin Precursor cDNAs in the Masu Salmon, Oncorhynchus Masou: Evolution of Neurohypophysial Hormone Precursors