HORDB

ID: hor000062
Uniprot ID: E9H8T6
Protein name: Inotocin
Gene name: NA
Organism: Daphnia pulex (Water flea)
Family: Vasopressin/oxytocin family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Daphnia (genus), Daphniidae (family), Anomopoda (infraorder), Cladocera (suborder), Diplostraca (order), Phyllopoda (subclass), Branchiopoda (class), Crustacea (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005184 neuropeptide hormone activity; GO:0005185 neurohypophyseal hormone activity
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region; GO:0005615 extracellular space; GO:0030141 secretory granule

Sequence: CFITNCPPG
Length: 9(26-34)
Propeptide: MAGLWTFCLIALSMTEMIIPLTAKPCFITNCPPGGKRSSQLVEPSSYLECAPCGPAGKGTCLGANLCCGSHFGCFFKTEETNVCLLTNLKSTQICNQHFWKTDLKSASCSLNGDKIDGICVADLLCCSLGNLPQDDL
Signal peptide: MAGLWTFCLIALSMTEMIIPLTA
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor000062_AF2.pdb

hor000062_ESM.pdb

Mass:	109400	Formula:	C41H62N10O12S2
Absent amino acids:	ADEHKLMQRSVWY	Common amino acids:	CP
pI:	5.84	Basic residues:	0
Polar residues:	5	Hydrophobic residues:	2
Hydrophobicity:	50	Boman Index:	219
Half-Life:	1.2 hour	Half-Life Yeast:	>20 hour
Half-Life E.Coli:	>10 hour	Aliphatic Index	43.33
Instability Index:	3178.89	Extinction Coefficient cystines:	125
Absorbance 280nm:	15.63

PubMed ID: 21830762
Title: Genomics, Transcriptomics, and Peptidomics of Daphnia Pulex Neuropeptides and Protein Hormones